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Is a common and serious brain disease.
More than 5 million Americans now have Alzheimer’s.
Alzheimer’s disease is a progressive, ultimately fatal, disorder in which certain types of nerve cells in particular areas of the brain degenerate and die for unknown reasons.
Vulnerable brain regions include the amygdala as well as the hippocampus and areas around the hippocampus, and affected cell populations include cortical pathways involved in catecholaminergic, seritonergic and cholinergic transmission. Advancing pathology is believed to underlie the classic clinical presentation of memory deficits followed by gradual erosion of judgment, reasoning ability, verbal fluency and other cognitive skills.
Pathology
The two "hallmark" Alzheimer lesions observable at autopsy – first described by German neuropsychiatrist Alois Alzheimer in 1906 – are amyloid plaques and neurofibrillary tangles. Plaques are extracellular deposits of abnormally processed amyloid precursor protein, and tangles are intracellular accumulations of the cytoskeletal protein tau.
Researchers now recognize that development of plaques and tangles may represent a fairly late-stage in the disease process that may or may not reflect the fundamental biochemical disruptions at work in Alzheimer’s. Although the "amyloid hypothesis," which assigns a central causative role to abnormal amyloid processing, remains the most widely embraced theory, other active areas of research include tau, inflammation, disruptions of cell signaling pathways and cardiovascular risk factors.
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USAGE: For the relief of toxicity to the brain, metal detoxification, enhances circulation to the brain, increases oxygen to the brain, enhances memory, enhances brain function, for senility, helps balance endocrine system, helps in regenerating nerves.
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